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IC 87361
CAS No. 404011-02-5
IC 87361( IC87361 )
Catalog No. M14384 CAS No. 404011-02-5
IC 87361 is a potent and selective DNA-PK inhibitor with IC50 of 34 nM, shows >50-fold selectivity over p110β.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 873 | Get Quote |
|
| 50MG | 1782 | Get Quote |
|
| 100MG | 2250 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
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| 500MG | Get Quote | Get Quote |
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| 1G | Get Quote | Get Quote |
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Biological Information
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Product NameIC 87361
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NoteResearch use only, not for human use.
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Brief DescriptionIC 87361 is a potent and selective DNA-PK inhibitor with IC50 of 34 nM, shows >50-fold selectivity over p110β.
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DescriptionIC 87361 is a potent and selective DNA-PK inhibitor with IC50 of 34 nM, shows >50-fold selectivity over p110β; enhances radiation sensitivity in wild-type C57BL6 endothelial cells; induces radiosensitization of tumor microvasculature in wild-type mice.
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In Vitro——
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In Vivo——
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SynonymsIC87361
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PathwayCell Cycle/DNA Damage
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TargetDNA-PK
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RecptorDNA-PK
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Research Area——
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Indication——
Chemical Information
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CAS Number404011-02-5
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Formula Weight323.348
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Molecular FormulaC19H17NO4
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Purity>98% (HPLC)
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Solubility——
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SMILES——
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Chemical Name5-hydroxy-7-morpholino-2-phenyl-4H-chromen-4-one
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Kashishian A, et al. Mol Cancer Ther. 2003 Dec;2(12):1257-64.
2. Shinohara ET, et al. Cancer Res. 2005 Jun 15;65(12):4987-92.
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